RM-TRS / Tissue, repair and matrix signalling
Livagen
Also known as: KEDA peptide · Lys-Glu-Asp-Ala
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Livagen is identified as the KEDA tetrapeptide. Its exact terminal and salt form must still be part of every material record.
Evidence position
Direct organ-culture and ex-vivo research supports Grade C. The publication stream is narrow and predominantly preclinical.
What the record does not establish
The record does not establish a controlled human outcome, an approved use or the identity and quality of a supplier lot.
Sources
- 01Livagen compound recordPubChem
- Shows
- Registry identity, KEDA sequence, formula and molecular mass
- Does not show
- Registry identity does not authenticate a supplier sample
- 02Livagen in organotypic liver culturePubMed
- Shows
- Direct organ-culture study naming the tetrapeptide
- Does not show
- Rat tissue culture and Russian-language publication; not a human outcome
- 03Peptide bioregulators and cultured lymphocyte chromatinPubMed
- Shows
- Ex-vivo lymphocyte study including Livagen
- Does not show
- Cultured cells from older donors; not an intervention in living participants
- 04Livagen market listingCore Peptides
- Shows
- Current research-market use of the Livagen and KEDA names
- Does not show
- Supplier copy does not validate sequence, lot or biological claims
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Livagen
- CID
- 87919683
- Formula
- C18H31N5O9
- Mass
- 461.5
PUBMED / FOUND RECORDS
- [Genomic instability in atherosclerosis].Georgian medical news / 2014 NovPMID 25541832
- Tissue-specific effects of peptides.Bulletin of experimental biology and medicine / 2001 AugPMID 11713572 / DOI 10.1023/a:1013058701974
- Effects of short peptides on lymphocyte chromatin in senile subjects.Bulletin of experimental biology and medicine / 2004 JanPMID 15085253 / DOI 10.1023/b:bebm.0000024393.40560.05
- Activation of pericentromeric and telomeric heterochromatin in cultured lymphocytes from old individuals.Annals of the New York Academy of Sciences / 2007 AprPMID 17460203 / DOI 10.1196/annals.1395.043
- [Effect of peptide bioregulator and cobalt ions on the activity of NORs and associations of acrocentric chromosomes in lymphocytes of patients with hypertrophic cardiomyopathy and their relatives].Georgian medical news / 2014 SepPMID 25341254