RM-IMM / Immune and host-defense signaling
Vilon
Also known as: KE peptide · Lys-Glu
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Vilon is the dipeptide Lys-Glu in the cited literature. The two-residue sequence is not unique enough to use as a search term without the Vilon context.
Evidence position
Direct cell-level research supports Grade C. The evidence is preclinical and concentrated in one research lineage.
What the record does not establish
Cell-signaling results do not establish a human outcome, route, dose or the identity and purity of a commercial sample.
Sources
- 01Lysylglutamic acid compound recordPubChem
- Shows
- Registry identity and formula for Lys-Glu
- Does not show
- Registry identity does not establish activity or product quality
- 02Short peptides in a human monocyte/macrophage cell modelPubMed
- Shows
- Defines Vilon as Lys-Glu and reports direct THP-1 cell findings
- Does not show
- In-vitro leukemia-derived cell line; not a clinical outcome study
- 03KE peptide and aging-related gene expressionPubMed
- Shows
- Direct cell-level research using the KE peptide
- Does not show
- Laboratory endpoint from one research stream
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Lysylglutamic acid
- CID
- 7010502
- Formula
- C11H21N3O5
- Mass
- 275.30
PUBMED / FOUND RECORDS
- Inhibitory effect of peptide vilon on the development of induced rat urinary bladder tumors in rats.Bulletin of experimental biology and medicine / 2001 JunPMID 11586406 / DOI 10.1023/a:1012354603132
- Anti-aging peptide bioregulators induce reactivation of chromatin.Georgian medical news / 2006 AprPMID 16705247
- Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people.Biogerontology / 2004PMID 15105581 / DOI 10.1023/B:BGEN.0000025070.90330.7f
- Tissue-specific effects of peptides.Bulletin of experimental biology and medicine / 2001 AugPMID 11713572 / DOI 10.1023/a:1013058701974
- Effect of peptide Vilon on the content of transforming growth factor-beta and permeability of microvessels during experimental chronic renal failure.Bulletin of experimental biology and medicine / 2005 JanPMID 16142267 / DOI 10.1007/s10517-005-0202-9