RM-MET / Metabolic and incretin signalling
Pancragen
Also known as: KEDW peptide · Lys-Glu-Asp-Trp
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Pancragen is identified in the cited paper as Lys-Glu-Asp-Trp. Market descriptions that omit the sequence, termini or salt form remain incomplete.
Evidence position
Grade C reflects direct cell-culture evidence. No human intervention study for the exact synthetic tetrapeptide was identified in the current indexed search.
What the record does not establish
A gene-expression result in cultured cells does not establish a human outcome, an approved use or the quality of a supplier sample.
Sources
- 01Tissue-specific stimulation of cell differentiation by short peptidesPubMed
- Shows
- Defines pancragen as Lys-Glu-Asp-Trp and reports gene-expression findings in cultured human pancreatic cells
- Does not show
- Cell-culture study from one research group; not a human outcome trial
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBMED / FOUND RECORDS
- Peptides tissue-specifically stimulate cell differentiation during their aging.Bulletin of experimental biology and medicine / 2012 MayPMID 22808515 / DOI 10.1007/s10517-012-1664-1
- [Correction of impaired glucose tolerance using tetrapeptide (Pancragen) in old female rhesus monkeys].Advances in gerontology = Uspekhi gerontologii / 2015PMID 28509500
- Prospects of using pancragen for correction of metabolic disorders in elderly people.Bulletin of experimental biology and medicine / 2011 AugPMID 22448364 / DOI 10.1007/s10517-011-1354-4
- Effects of pancragen on the differentiation of pancreatic cells during their ageing.Bulletin of experimental biology and medicine / 2013 FebPMID 23486591 / DOI 10.1007/s10517-013-1987-6
- Effect of pancragen on blood glucose level, capillary permeability and adhesion in rats with experimental diabetes mellitus.Bulletin of experimental biology and medicine / 2007 OctPMID 18642713 / DOI 10.1007/s10517-007-0377-3