ML-SYS / 2026.07NON-CLINICAL RESEARCH MATERIALSORIGIN DECLARED BY LOT

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RM-END / Endocrine and peptide-hormone analogs

Glucagon

Also known as: Human glucagon · Gvoke

Approved comparator exists

Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.

What this is

Glucagon is an endogenous 29-amino-acid peptide hormone. Finished products use defined formulations and delivery systems.

Evidence position

The regulated product record supports Grade A for the named products.

What the record does not establish

The label does not establish identity, potency or stability for another glucagon sample.

Sources

  • 01
    Gvoke and Gvoke VialDx prescribing informationDailyMed / U.S. National Library of Medicine
    Shows
    Current U.S. label for defined synthetic glucagon presentations
    Does not show
    Does not authenticate another formulation, concentration or source

External database index

LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE

Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.

PUBMED / FOUND RECORDS

  1. Hepatic glucagon action: beyond glucose mobilization.Physiological reviews / 2024 Jul 1PMID 38300523 / DOI 10.1152/physrev.00028.2023
  2. 100 years of glucagon and 100 more.Diabetologia / 2023 AugPMID 37367959 / DOI 10.1007/s00125-023-05947-y
  3. The past, present, and future physiology and pharmacology of glucagon.Cell metabolism / 2022 Nov 1PMID 36323234 / DOI 10.1016/j.cmet.2022.10.001
  4. A famsin-glucagon axis mediates glucose homeostasis.Cell metabolism / 2025 Mar 4PMID 39706194 / DOI 10.1016/j.cmet.2024.11.008
  5. Glucagon Physiology. / 2000PMID 25905350

CLINICALTRIALS.GOV / FOUND RECORDS

  1. Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different TreatmentsCOMPLETED / NO PHASE / Novo Nordisk A/SNCT04809311 / DIRECT intervention MATCH: Glucagon
  2. Evaluate the Immunogenicity of a Novel Glucagon FormulationCOMPLETED / PHASE3 / Eli Lilly and CompanyNCT01959334 / DIRECT intervention MATCH: Glucagon
  3. Relationship Between Changes in Gut Hormones After Gastric Bypass and Gastric Banding and Improvements in DiabetesCOMPLETED / NO PHASE / University of PennsylvaniaNCT01153438 / DIRECT title MATCH: Glucagon
  4. Safety Study of Repeated Doses of Glucagon on Animal Starch in the LiverCOMPLETED / NA / Legacy Health SystemNCT01986231 / DIRECT intervention MATCH: Glucagon
  5. Role of Aprotinin in Glucagon Degradation, Measurement by Radioimmunoactive Method (RIA) I125COMPLETED / NA / University Hospital, Gentofte, CopenhagenNCT01436734 / DIRECT title MATCH: Glucagon

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