RM-END / Endocrine and peptide-hormone analogs
Gonadorelin
Also known as: Gonadotropin-releasing hormone · GnRH · Gonadoliberin · LHRH
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Gonadorelin is the ten-residue peptide also called gonadotropin-releasing hormone. Continuous exposure, pulsatile exposure and single stimulation testing are not interchangeable experimental conditions.
Evidence position
Direct human endocrine-response work supports Grade B. The currently cited regulated comparator is a veterinary product and is labeled for cattle only.
What the record does not establish
Sequence identity does not transfer the veterinary product’s concentration, preservative system, sterility, route or label to another sample.
Sources
- 01Factrel gonadorelin veterinary labelDailyMed / U.S. National Library of Medicine
- Shows
- Defined sequence, formulation and current FDA veterinary-label context
- Does not show
- For cattle only; does not establish a human indication or qualify another formulation
- 02Human gonadorelin stimulation-test studyPubMed
- Shows
- Human pituitary LH and FSH responses after a defined gonadorelin stimulation test
- Does not show
- Diagnostic-response study; not long-term effectiveness or supplier verification
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Gonadorelin
- CID
- 638793
- Formula
- C55H75N17O13
- Mass
- 1182.3
PUBMED / FOUND RECORDS
- Endometriosis.BMJ clinical evidence / 2010 Aug 13PMID 21418683
- Endometriosis.BMJ clinical evidence / 2007 Mar 1PMID 19454060
- Menorrhagia.BMJ clinical evidence / 2012 Jan 18PMID 22305976
- Breast pain.BMJ clinical evidence / 2011 Jan 17PMID 21477394
- Premenstrual syndrome.BMJ clinical evidence / 2007 May 1PMID 19454075
CLINICALTRIALS.GOV / FOUND RECORDS
- GnRH Therapy on Cognition in Down SyndromeRECRUITING / PHASE2, PHASE3 / Nelly PitteloudNCT04390646 / DIRECT intervention MATCH: Gonadorelin