ML-SYS / 2026.07NON-CLINICAL RESEARCH MATERIALSORIGIN DECLARED BY LOT

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RM-END / Endocrine and peptide-hormone analogs

Goserelin

Also known as: Goserelin acetate ยท Zoladex

Approved comparator existsEvidence grade A: Approved comparator exists

Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.

What this is

Goserelin is a synthetic GnRH agonist. The approved comparator is supplied as a controlled-release implant.

Evidence position

The regulated implant record supports Grade A for that finished product only.

What the record does not establish

The label does not establish identity, release behavior, strength or quality for another formulation or sample.

Sources

  • 01
    Zoladex prescribing informationDailyMed / U.S. National Library of Medicine
    Shows
    Current U.S. label for a defined goserelin implant
    Does not show
    Does not authenticate a free peptide, vial or different delivery system

External database index

LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE

Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.

PUBMED / FOUND RECORDS

  1. Goserelin. / 2012PMID 31644049
  2. [Goserelin].Ugeskrift for laeger / 1990 Apr 30PMID 2140473
  3. Efficacy and safety of LY01005 versus goserelin implant in Chinese patients with prostate cancer: A multicenter, randomized, open-label, phase III, non-inferiority trial.Chinese medical journal / 2023 May 20PMID 37010251 / DOI 10.1097/CM9.0000000000002638
  4. Clinical pharmacokinetics of goserelin.Clinical pharmacokinetics / 2000 JulPMID 10926349 / DOI 10.2165/00003088-200039010-00003
  5. Goserelin.Nursing times / 2006 Jan 17-23PMID 16440976

CLINICALTRIALS.GOV / FOUND RECORDS

  1. Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS TrialRECRUITING / PHASE2 / University of Michigan Rogel Cancer CenterNCT07158021 / DIRECT intervention MATCH: Goserelin
  2. Goserelin, Flutamine, and Radiation Therapy in Treating Patients With Locally Advanced Prostate CancerCOMPLETED / PHASE3 / Radiation Therapy Oncology GroupNCT00767286 / DIRECT intervention MATCH: Goserelin
  3. Androgen Deprivation Therapy or Androgen Deprivation Therapy Plus Definitive Treatment (Radiation or Surgery)UNKNOWN / PHASE2 / Fudan UniversityNCT02742675 / DIRECT intervention MATCH: Goserelin
  4. Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed TumorsACTIVE_NOT_RECRUITING / PHASE2 / Xiao X. Wei, MDNCT04126070 / DIRECT intervention MATCH: Goserelin
  5. Prostate Adenocarcinoma TransCutaneous HormonesUNKNOWN / PHASE3 / University College, LondonNCT00303784 / DIRECT intervention MATCH: Goserelin

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