RM-TRS / Tissue, repair and matrix signalling
Acetyl Octapeptide-3
Also known as: SNAP-8 ยท Acetyl Glutamyl Heptapeptide-3
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Acetyl octapeptide-3 is the INCI ingredient marketed as SNAP-8. It is not acetyl hexapeptide-8, despite both being positioned around SNAP-25-related cosmetic concepts.
Evidence position
The exact chemical record is clear, but the independent clinical record is weak. That supports Grade D.
What the record does not establish
Related Argireline studies, manufacturer panels and combination creams do not prove the performance or identity of a SNAP-8-labelled powder.
Sources
- 01Acetyl Octapeptide-3 compound recordPubChem
- Shows
- Registry identity, formula and molecular properties
- Does not show
- Registry identity does not establish efficacy or lot quality
- 02SNAP-8 market listingCore Peptides
- Shows
- Current research-market use of the SNAP-8 and Acetyl Octapeptide-3 names
- Does not show
- Supplier claims are not independent clinical evidence
- 03Current Approaches in Cosmeceuticals: Peptides, Biotics and Marine BiopolymersPolymers
- Shows
- Peer-reviewed review that identifies Acetyl Octapeptide-3/SNAP-8 and summarizes formulation and delivery research
- Does not show
- Review-level evidence; it does not authenticate a raw material or isolate every formulation effect
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Acetyl octapeptide-3
- CID
- 71587832
- Formula
- C42H72N16O15S
- Mass
- 1073.2
PUBMED / FOUND RECORDS
- Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study.Journal of cosmetic dermatology / 2020 FebPMID 31134751 / DOI 10.1111/jocd.13009
- Clinical Safety and Efficacy Evaluation of a Dissolving Microneedle Patch Having Dual Anti-Wrinkle Effects With Safe and Long-Term Activities.Annals of dermatology / 2024 AugPMID 39082657 / DOI 10.5021/ad.23.136