RM-TRS / Tissue, repair and matrix signalling
SYN-AKE
Also known as: Dipeptide Diaminobutyroyl Benzylamide Diacetate · beta-Ala-Pro-Dab-NHBn diacetate
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
SYN-AKE is a defined synthetic diacetate ingredient. It was designed by analogy to a venom-peptide effect, but it is not Waglerin-1 and does not contain venom.
Evidence position
Small human topical research supports a limited Grade B. The evidence remains tied to defined formulations.
What the record does not establish
The literature does not validate a raw supplier lot, an injectable route or equivalence across concentrations and salt forms.
Sources
- 01SYN-AKE diacetate compound recordPubChem
- Shows
- Registry identity, salt composition, formula and synonyms
- Does not show
- Registry identity does not establish topical performance
- 02Facial-expression wrinkle studyInternational Journal of Peptide Research and Therapeutics
- Shows
- Peer-reviewed study directly discussing the marketed SYN-AKE ingredient
- Does not show
- Small cosmetic study; formulation and commercial relationships limit generalization
- 03SYN-AKE market listingCore Peptides
- Shows
- Current research-market use of the SYN-AKE name
- Does not show
- Supplier copy is not independent evidence or lot verification
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Dipeptide diaminobutyroyl benzylamide diacetate
- CID
- 71465152
- Formula
- C23H37N5O7
- Mass
- 495.6
PUBMED / FOUND RECORDS
- Anti-aging activity of Syn-Ake peptide by in silico approaches and in vitro tests.Journal of biomolecular structure & dynamics / 2024 JulPMID 37349941 / DOI 10.1080/07391102.2023.2223681
- The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies.International journal of cosmetic science / 2026 Feb 11PMID 41668671 / DOI 10.1111/ics.70087