Prostamax

Also known as: KEDP peptide · Lys-Glu-Asp-Pro

Preclinical evidence

Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.

What this is

Prostamax is identified in the indexed record as Lys-Glu-Asp-Pro, or KEDP. The exact terminal form and counterion still have to be supplied for a commercial material.

Evidence position

Direct cultured-cell and organotypic research supports Grade C. Human cells do not make these human intervention trials; the measured endpoints are chromatin structure and gene activity outside the body.

What the record does not establish

The literature does not establish a clinical prostate outcome, route, dose, pharmacokinetics, safety or supplier-lot identity and purity.

Sources

01
Chromatin effects of Lys-Glu-Asp-Pro in cells from older adultsPubMed
Shows
Names Prostamax and Lys-Glu-Asp-Pro in the same record and reports cultured-cell chromosome measurements
Does not show
Ex-vivo cell study; the participants were cell donors, not recipients in a clinical intervention
02
Prostamax and heterochromatin in human lymphocytesPubMed
Shows
Direct exact-name laboratory record using cultured human lymphocytes
Does not show
Biophysical chromatin measurements only; not a clinical endpoint
03
Short-peptide effects on lymphocyte chromatinPubMed
Shows
Includes Prostamax among peptides studied in leukocytes from older adults
Does not show
Cellular chromatin findings do not establish organ-specific or clinical effects

External database index

LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE

Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.

PUBMED / FOUND RECORDS

Effects of short peptides on lymphocyte chromatin in senile subjects.Bulletin of experimental biology and medicine / 2004 JanPMID 15085253 / DOI 10.1023/b:bebm.0000024393.40560.05
[Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro)].Georgian medical news / 2012 NovPMID 23221144
[The influence of the peptide bioregulator prostamax on heterochromatin of human lymphocytes in situ].Biofizika / 2004 Nov-DecPMID 15612551
[The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats].Advances in gerontology = Uspekhi gerontologii / 2006PMID 17152728
Microcalorimetric study of human blood lymphocytes culture at presence of copper, cadmium and prostamax.Georgian medical news / 2009 MarPMID 19359734

Related compounds

RM-END