RM-GHA / Growth-hormone-axis signalling
GHRP-2
Also known as: Pralmorelin · KP-102 · Growth hormone-releasing peptide 2
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
GHRP-2 is a synthetic peptide agonist at the growth-hormone secretagogue receptor. Pralmorelin and KP-102 are common names in the literature.
Evidence position
Human pharmacology studies support Grade B. That grade describes the molecule’s published record, not a quality or safety grade for independently supplied material.
What the record does not establish
The research does not authenticate a supplier, vial or lot and does not support extrapolation beyond the studied formulation and protocol.
Sources
- 01GHRP-2, like ghrelin, increases food intake in healthy menPubMed
- Shows
- Small controlled human infusion study measuring food intake and endocrine effects
- Does not show
- Seven healthy men, acute exposure and a controlled research preparation
- 02Pralmorelin development summaryPubMed
- Shows
- Development and diagnostic-research summary for pralmorelin/GHRP-2
- Does not show
- Does not establish current U.S. approval or product equivalence
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Pralmorelin
- CID
- 6918245
- Formula
- C45H55N9O6
- Mass
- 818.0
PUBMED / FOUND RECORDS
- Ipamorelin, the first selective growth hormone secretagogue.European journal of endocrinology / 1998 NovPMID 9849822 / DOI 10.1530/eje.0.1390552
- Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN.Drugs in R&D / 2004PMID 15230633 / DOI 10.2165/00126839-200405040-00011
- The Safety and Efficacy of Growth Hormone Secretagogues.Sexual medicine reviews / 2018 JanPMID 28400207 / DOI 10.1016/j.sxmr.2017.02.004
- Growth hormone-releasing peptides.European journal of endocrinology / 1997 MayPMID 9186261 / DOI 10.1530/eje.0.1360445
- Determination of growth hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by liquid chromatography/electrospray ionization tandem mass spectrometry.Rapid communications in mass spectrometry : RCM / 2010 Jul 30PMID 20552695 / DOI 10.1002/rcm.4619