ML-SYS / 2026.07NON-CLINICAL RESEARCH MATERIALSORIGIN DECLARED BY LOT

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RM-MET / Metabolic and incretin signalling

AOD-9604

Also known as: Tyr-hGH 177-191

Preclinical evidenceEvidence grade C: Preclinical evidence

Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.

What this is

A synthetic fragment of human growth hormone. The published record is preclinical and metabolic in nature.

Evidence position

Grade C. Preclinical and mechanistic evidence only. FDA lists AOD-9604 among bulk substances that may present significant safety risks.

What the record does not establish

Published research about a molecule is not a test of any particular vial. Identity, purity, strength and microbiological quality are established by lot-level analytical records tied to a matched sample — not by the literature, and not by the presence of an approved comparator.

Where a lot-level record exists it is published on the evidence page and linked from the product. Where it does not exist, the record says so.

Sources

External database index

LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE

Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.

PUBMED / FOUND RECORDS

  1. AOD-9604 Metabolic.Current opinion in investigational drugs (London, England : 2000) / 2004 AprPMID 15134286
  2. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews / 2026 Jan 1PMID 41490200 / DOI 10.5435/JAAOSGlobal-D-25-00236
  3. Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.Sports medicine (Auckland, N.Z.) / 2026 Apr 12PMID 41966639 / DOI 10.1007/s40279-026-02437-0
  4. AOD-9604 does not influence the WADA hGH isoform immunoassay.Drug testing and analysis / 2013 Nov-DecPMID 24124033 / DOI 10.1002/dta.1557
  5. Obesity drugs in clinical development.Current opinion in investigational drugs (London, England : 2000) / 2006 AprPMID 16625817

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