RM-GHA / Growth-hormone-axis signalling
Sermorelin
Also known as: GRF 1-29
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
A 29-amino-acid GHRH analog. A product containing sermorelin acetate held FDA approval historically.
Evidence position
Grade A, historical. The correct phrasing is ‘historically approved comparator’ — not ‘FDA approved product’. The prior approval does not validate current third-party material.
What the record does not establish
Published research about a molecule is not a test of any particular vial. Identity, purity, strength and microbiological quality are established by lot-level analytical records tied to a matched sample — not by the literature, and not by the presence of an approved comparator.
Where a lot-level record exists it is published on the evidence page and linked from the product. Where it does not exist, the record says so.
Sources
- 01Geref approval packageFDA Access Data
- Shows
- A historical approval existed
- Does not show
- Product withdrawn; does not validate current material
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Sermorelin
- CID
- 16132413
- Formula
- C149H246N44O42S
- Mass
- 3357.9
PUBMED / FOUND RECORDS
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews / 2026 Jan 1PMID 41490200 / DOI 10.5435/JAAOSGlobal-D-25-00236
- Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.Sports medicine (Auckland, N.Z.) / 2026 Apr 12PMID 41966639 / DOI 10.1007/s40279-026-02437-0
- Advances in the detection of growth hormone releasing hormone synthetic analogs.Drug testing and analysis / 2021 NovPMID 34665524 / DOI 10.1002/dta.3183
- Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.Translational andrology and urology / 2020 MarPMID 32257855 / DOI 10.21037/tau.2019.11.30
- In-house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH-related peptides.Biomedical chromatography : BMC / 2023 DecPMID 37688464 / DOI 10.1002/bmc.5741