RM-TRS / Tissue, repair and matrix signalling
PTD-DBM
Also known as: Protein transduction domain–Dishevelled binding motif · RRRRRRRRGGGGRKTGHQICKFRKC
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
PTD-DBM is an engineered multi-domain peptide, not a naturally occurring short peptide. Its terminal and cysteine redox state are part of identity.
Evidence position
Direct cellular and animal research supports Grade C. The record has not progressed to qualifying human outcomes.
What the record does not establish
The record does not establish clinical effectiveness, approved use or the identity and quality of any seller’s material.
Sources
- 01PTD-DBM compound recordPubChem
- Shows
- Registry sequence, formula and molecular mass
- Does not show
- Registry identity does not establish folding, redox state or biological activity
- 02CXXC5 and cutaneous wound-healing studyPubMed
- Shows
- Direct cell and mouse work using PTD-DBM
- Does not show
- Preclinical wound model; not a human outcome study
- 03PTD-DBM market listingCore Peptides
- Shows
- Current research-market use of the PTD-DBM name
- Does not show
- Supplier copy is not independent evidence or lot verification
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Ptd-dbm
- CID
- 176453931
- Formula
- C124H225N61O28S2
- Mass
- 3082.6
PUBMED / FOUND RECORDS
- Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies.Cells / 2025 May 26PMID 40497955 / DOI 10.3390/cells14110779
- CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD(2).Cells / 2023 Feb 9PMID 36831222 / DOI 10.3390/cells12040555
- Adhesive Hydrogel Patch-Mediated Combination Drug Therapy Induces Regenerative Wound Healing through Reconstruction of Regenerative Microenvironment.Advanced healthcare materials / 2023 JulPMID 36854308 / DOI 10.1002/adhm.202203094
- The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing.The Journal of experimental medicine / 2015 Jun 29PMID 26056233 / DOI 10.1084/jem.20141601