RM-TRS / Tissue, repair and matrix signalling
BPC-157
Also known as: Body Protection Compound-157 · PL 14736
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
A synthetic pentadecapeptide derived from a gastric protein sequence. The published record is predominantly preclinical.
Evidence position
Grade C. Preclinical context only. FDA lists BPC-157 among substances with potential significant safety risks and limited human safety information.
What the record does not establish
Published research about a molecule is not a test of any particular vial. Identity, purity, strength and microbiological quality are established by lot-level analytical records tied to a matched sample — not by the literature, and not by the presence of an approved comparator.
Where a lot-level record exists it is published on the evidence page and linked from the product. Where it does not exist, the record says so.
Sources
- 01Tendon fibroblast outgrowth studyPubMed
- Shows
- Preclinical cell work
- Does not show
- Not a human outcome study
- 02Bulk drug substances that may present significant safety risksU.S. Food and Drug Administration
- Shows
- Regulator safety position
- Does not show
- Not a quality assessment of any vial
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Bpc-157
- CID
- 9941957
- Formula
- C62H98N16O22
- Mass
- 1419.5
PUBMED / FOUND RECORDS
- Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.Pharmaceuticals (Basel, Switzerland) / 2025 Jan 30PMID 40005999 / DOI 10.3390/ph18020185
- Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery / 2025 NovPMID 40756949 / DOI 10.1177/15563316251355551
- Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.Cell and tissue research / 2019 AugPMID 30915550 / DOI 10.1007/s00441-019-03016-8
- Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.Alternative therapies in health and medicine / 2021 JulPMID 34324435
- Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.Frontiers in pharmacology / 2021PMID 34267654 / DOI 10.3389/fphar.2021.627533
CLINICALTRIALS.GOV / FOUND RECORDS
- PCO-02 - Safety and Pharmacokinetics TrialUNKNOWN / PHASE1 / PharmaCotherapia d.o.o.NCT02637284 / DIRECT intervention MATCH: BPC-157
- BPC 157 for Acute Hamstring Muscle Strain RepairRECRUITING / PHASE2 / Hudson BiotechNCT07437547 / DIRECT intervention MATCH: BPC-157