RM-TRS / Tissue, repair and matrix signalling
KPV
Also known as: alpha-MSH 11-13
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
A tripeptide corresponding to the C-terminal fragment of alpha-MSH. Evidence located is preclinical.
Evidence position
Grade C. Preclinical-only family. Exact sequence and an analytical reference standard are required.
What the record does not establish
Published research about a molecule is not a test of any particular vial. Identity, purity, strength and microbiological quality are established by lot-level analytical records tied to a matched sample — not by the literature, and not by the presence of an approved comparator.
Where a lot-level record exists it is published on the evidence page and linked from the product. Where it does not exist, the record says so.
Sources
- 01
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
5-Phenyl-2-keto-valeric acid
- CID
- 13294447
- Formula
- C11H12O3
- Mass
- 192.21
PUBMED / FOUND RECORDS
- Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.Tissue & cell / 2025 AugPMID 40073467 / DOI 10.1016/j.tice.2025.102837
- Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer.Oncogene / 2023 JunPMID 37161053 / DOI 10.1038/s41388-023-02703-9
- NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development.Cell death and differentiation / 2026 FebPMID 40935835 / DOI 10.1038/s41418-025-01578-5
- Peptide Receptor-Targeted Fluorescent Probe: Visualization and Discrimination between Chronic and Acute Ulcerative Colitis.ACS applied materials & interfaces / 2017 Apr 19PMID 28349696 / DOI 10.1021/acsami.7b00936
- A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.Acta biomaterialia / 2022 Apr 15PMID 35245681 / DOI 10.1016/j.actbio.2022.02.039