RM-NBS / Neurobehavioural and neuroendocrine signalling
DSIP
Also known as: Delta sleep-inducing peptide
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
A nonapeptide first characterised in the 1970s. The human literature is old and limited.
Evidence position
Grade B, legacy. Evidence should be marked as legacy and limited. No sleep-improvement claim is supportable.
What the record does not establish
Published research about a molecule is not a test of any particular vial. Identity, purity, strength and microbiological quality are established by lot-level analytical records tied to a matched sample — not by the literature, and not by the presence of an approved comparator.
Where a lot-level record exists it is published on the evidence page and linked from the product. Where it does not exist, the record says so.
Sources
- 01Controlled sleep studyPubMed
- Shows
- Historical human data
- Does not show
- Legacy literature; small and dated
- 02Insomnia clinical studyPubMed
- Shows
- Historical human data
- Does not show
- Legacy literature; small and dated
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Delta Sleep-Inducing Peptide
- CID
- 68816
- Formula
- C35H48N10O15
- Mass
- 848.8
PUBMED / FOUND RECORDS
- Delta sleep-inducing peptide (DSIP): a still unresolved riddle.Journal of neurochemistry / 2006 AprPMID 16539679 / DOI 10.1111/j.1471-4159.2006.03693.x
- Die Anfänge moderner Schlafforschung.Zurcher medizingeschichtliche Abhandlungen / 1994PMID 11630267
- Delta-sleep-inducing peptide (DSIP): an update.Peptides / 1986 Nov-DecPMID 3550726 / DOI 10.1016/0196-9781(86)90148-8
- Biochemical regulation of non-rapid-eye-movement sleep.Frontiers in bioscience : a journal and virtual library / 2003 May 1PMID 12700031 / DOI 10.2741/1033
- Production and immunohistochemical application of monoclonal antibodies against delta sleep-inducing peptide.Journal of chemical neuroanatomy / 1992 Nov-DecPMID 1476667 / DOI 10.1016/0891-0618(92)90005-b