RM-CVS / Coagulation and vascular signalling
Angiotensin II
Also known as: Giapreza · Angiotensin II acetate · Angiotensin-2
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Angiotensin II is an endogenous eight-amino-acid vasoactive peptide. The labeled comparator is a specific synthetic human angiotensin II acetate concentrate for intravenous dilution.
Evidence position
The regulated finished product and controlled human evidence support Grade A for the exact labeled presentation.
What the record does not establish
The finished-product record does not authenticate a separately sourced peptide or establish another material’s identity, potency, sterility or concentration.
Sources
- 01Angiotensin II compound recordPubChem
- Shows
- Registry identity, sequence-derived structure, formula and synonyms for angiotensin II
- Does not show
- Does not establish a finished-product formulation, concentration or lot quality
- 02Giapreza prescribing informationDailyMed / U.S. National Library of Medicine
- Shows
- U.S. label for a defined intravenous angiotensin II concentrate
- Does not show
- Does not qualify another source, acetate content, concentration or presentation
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Angiotensin Ii
- CID
- 172198
- Formula
- C50H71N13O12
- Mass
- 1046.2
PUBMED / FOUND RECORDS
- Angiotensin II.Intensive care medicine / 2024 FebPMID 38189932 / DOI 10.1007/s00134-023-07290-7
- Mechanosensitive Angiotensin II Receptor Signaling in Pressure-Induced Vasoconstriction.Journal of the American Heart Association / 2022 Feb 15PMID 35156384 / DOI 10.1161/JAHA.121.024740
- [Angiotensin II-receptor blockers].Duodecim; laaketieteellinen aikakauskirja / 2005PMID 15907084
- Angiotensin II receptor research.Current pharmaceutical design / 2013PMID 23176222 / DOI 10.2174/1381612811319170001
- Angiotensin II-Real-Life Use and Literature Review.Medicina (Kaunas, Lithuania) / 2024 Sep 11PMID 39336524 / DOI 10.3390/medicina60091483
CLINICALTRIALS.GOV / FOUND RECORDS
- A Study of LJPC-501 in Pediatric Patients With HypotensionCOMPLETED / PHASE2 / La Jolla Pharmaceutical CompanyNCT03431077 / DIRECT intervention MATCH: Angiotensin II
- Angiotensin II in General AnesthesiaCOMPLETED / PHASE4 / Wake Forest University Health SciencesNCT03733145 / DIRECT intervention MATCH: Angiotensin II