RM-NUT / Nutrients and complex formulations
Vitamin B12 (cobalamin)
Grade describes the published research on the molecule. It is not a quality score, a safety score, or a release state.
What this is
Cobalamin exists in several forms — cyanocobalamin, methylcobalamin, hydroxocobalamin — which are not interchangeable for identity purposes.
Evidence position
Grade U until form and concentration are documented. An official cyanocobalamin label is a comparator, not evidence about a given product.
What the record does not establish
Published research about a molecule is not a test of any particular vial. Identity, purity, strength and microbiological quality are established by lot-level analytical records tied to a matched sample — not by the literature, and not by the presence of an approved comparator.
Where a lot-level record exists it is published on the evidence page and linked from the product. Where it does not exist, the record says so.
Sources
- 01Cyanocobalamin injection labelDailyMed (NLM)
- Shows
- Defines an approved comparator composition
- Does not show
- Does not identify any specific product's form or strength
External database index
LIVE DATABASE INDEX / SEPARATE FROM CURATED EVIDENCE
Records below come directly from public scientific databases. They help find relevant material, but do not affect the evidence grade until they are matched to the molecule and added to the curated source list.
PUBCHEM / IDENTITY
Vitamin B12
- CID
- 165339223
- Formula
- C63H88CoN14O14P
- Mass
- 1355.4
PUBMED / FOUND RECORDS
- Vitamin B12.British medical bulletin / 1956 JanPMID 13284304 / DOI 10.1093/oxfordjournals.bmb.a069516
- Vitamin B12 absorption.The American journal of clinical nutrition / 1958 May-JunPMID 13533318 / DOI 10.1093/ajcn/6.3.332
- Vitamin B12.Medical world / 1952 Jul 18PMID 14947385
- Late Life Vitamin B12 Deficiency.Clinics in geriatric medicine / 2019 AugPMID 31230733 / DOI 10.1016/j.cger.2019.03.004
- [VITAMIN B12].Deutsche medizinische Wochenschrift (1946) / 1957 Aug 2PMID 13461622 / DOI 10.1055/s-0028-1116868
CLINICALTRIALS.GOV / FOUND RECORDS
- Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With ObesityENROLLING_BY_INVITATION / NA / University of Sao PauloNCT05097365 / DIRECT intervention MATCH: Vitamin B12
- TRIM: Danish Form and Dose Study on Vitamin B12COMPLETED / NA / University of AarhusNCT02832726 / DIRECT intervention MATCH: Vitamin B12
- Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total GastrectomyCOMPLETED / PHASE2 / Yonsei UniversityNCT00699478 / DIRECT intervention MATCH: cobalamin
- Epigallocatechin Gallate and Other Antural Compounds in HPV InfectionsCOMPLETED / PHASE2 / Centro di Ricerca Clinica SalentinoNCT06098456 / DIRECT title MATCH: Vitamin B12
- Influence of Genetics on Vitamin Metabolism in Pregnant WomenCOMPLETED / NO PHASE / National Human Genome Research Institute (NHGRI)NCT00340366 / DIRECT title MATCH: cobalamin